International Peanut Allergy Prevention, 6 Years After the Learning Early About Peanut Study.

Abrams Elissa M, Shaker Marcus, Greenhawt Matthew, Mack Douglas P

The journal of allergy and clinical immunology. In practice · 2022 · PMID 34311123 · 인용 19

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Six years ago, the Learning Early About Peanut (LEAP) trial findings helped fundamentally shift the paradigm of peanut allergy prevention. Although the results of LEAP are well accepted, policy-makers, caregivers, and clinicians struggle with how best to implement and apply the study's key findings in clinical practice. Differences in guidelines highlight issues related to peanut allergy prevention implementation, including caregiver acceptability, cost, fidelity, feasibility, appropriateness, and adoption.

The goals of this rostrum are to review how the LEAP study has informed international peanut allergy prevention policy, as well as to review the strengths and ongoing controversies in peanut allergy prevention implementation.

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